Profound permanent alteration of the human genetic substance has become a reality, and while militarized modification of the human genome for warfighting or eugenics purposes is tightly controlled and policed, cosmetic and personal health modification is widespread for those who can afford it. The results of this may be seen among the most wealthy and privileged of Withmore City, whose aesthetic pursuits have pushed so far beyond the past inadequacies of cosmetic surgery that they may only be somewhat recognizable as human. This extreme modification of humanity has produced great social and political friction, with several different groups arising to either oppose modification entirely, or protest its exclusivity to the ultra-rich.
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