I know that blowing stuff up is highly controlled, but just think, wouldn't it be cool if the labs blew up if you weren't good at chemistry?
Bob is in his New Rose cube cooking up some v-202, when a violent explosion rips the room apart and sends shards of glass and a flaming body out the window and onto the pavement in front of the drome.
Maybe there shouldn't be consequences so drastic, but there should be, for an unskilled drug maker, rather than just a shitty batch of drugs that fucks people over.
Maybe the chemicals, if improperly mixed, could make some kind of gas that, depending on the potentcy, makes you pass out for a while, temporarily paralyzed, or die altogether.
That also opens up a whole new way of getting at your enemies, making this gas on purpose, and you could go as far as to slide a small tube underneath someone's door, paralyzing the people inside temporarily, knocking them unconscious, or even killing them, while the door gets kicked in, the code gets cracked, or whatever.
Of course, you could never add anything that could not be countered. There could be things like oxygen tanks and gas masks, if you're worried about getting killed in your cube.
That could add in a new thing to health, just add some messages to it when you get a bad batch of v-202, rather than 'He is in excellent condition' or 'He is suffering from a painful laceration and is laboring in intense pain' you could have 'His face is sunken, and he's got bags beneath his eyes.' You could tie this in with charisma, too. Maybe after having a bad batch of drugs, people puke at random intervals, depending on the severity of the poisoning, and you could even create an object called 'puddle of puke' that can't be picked up, but has to be cleaned with a verb. It could be like a corpse, and get worse and worse, until somebody cleans it. If you really wanted to go overboard, you could record what the people eat in a variable, and describe the puke according to that, 'The puddle of vomit seems to be comprised mostly of what appears to be bits of french fry, but also has some yellow and red that must have been pizza.' The puke could get nastier, until it's a puddle of rotting, half digested food. Maybe people will think twice before getting drunk or getting a fix.
I have much more to say, but I'm done raving now...