One thing the game has taught me over and over again is to take things on the chin and keep rolling. Most of the time it pays off, and even more in ways I don't expect it. I know I forget it all the time, and reinforcing it has been a major part of helping me enjoy the game more.
Ultimately, it's about the experience, and not any outcome.
Barring my own quasi-poetic bullshit, do you all have any other trite little adages or platitudes that've helped you learn to enjoy Sindome more and/or understand the weird and wild experience that is life in the Dome?