A major theme of cyberpunk is that the people in these stories are stuck living on the margins in a time and place where being an individual has never meant less, and they never really overcome that. At the end of Neuromancer, Case and Molly don't start a family and buy a house, they split up and he goes back to hacking while she winds up becoming some Yakuza heiress's bodyguard. They're not really any better off than when they started.
The power structures in the game, from the gangs on up through the megacorps, are incomprehensibly well established. The Sinners are not six teenagers with bats who somehow make all their money stealing gear from other gangs, they're hundreds strong and are the de facto government on their streets. People and businesses pay taxes to them in the same way you pay taxes where you live, and they get tangible benefits out of this.
NLM isn't a TV company, it's very nearly the sum total of the entire entertainment industry throughout the solar system and it wields more power than most nations on Earth. You can talk shit to their employees all you like but if the eye of Sauron ever looks directly at you, you're gone.
Anything you want to do that isn't in line with what organizations like this want you to be doing is going to cause friction. Cyberpunk stories are about people who don't fit into society causing just a little bit of trouble and then going to enormous lengths to try to avoid the consequences. Johnny Mnemonic's a great example - Johnny and Molly don't wipe out the Yakuza with their superior skills and live happily ever after, they trick one single assassin with a lot of help and then Johnny has to live out the rest of his life off the grid with a bunch of garbage eating dog splicers or he'll be supermurdered. He doesn't win, he escapes by the skin of his (canine) teeth.
If you lumped all the active PCs into one single group, there would be fewer of them than there are NPC TERRA agents, and even working together they would probably not realistically be able to do much about TERRA and who and what they are in the world - and TERRA is one of the weaker examples here.
So if you're frustrated, try to remember that you're not the hero. You're never meant to be anything more than the guy who maybe got away with something one time. I'm not saying players can't change shit but try to consider the scope instead of smallworlding with just the NPCs and PCs you see on screen.