A bunch of tabletop and literary examples for starters.
Billy Idol is a classic example of someone subverting gender expectations. He was certainly a male icon in his heyday but he was very feminine and highly sexualized in his presentation. He's what I think of whenever I see someone with the femboy shortdesc.
You can see similar themes of gender and sexuality in other works Sindome draws from. Lord Humungus in Road Warrior has two sections of his army called smegma-crazies and gayboy berserkers, and there's no shortage of twinky dudes, dykey lesbians, or trans characters in similar contemporary media. Look at the new romantics, the punks, the goths.
Part of that back then was the sleaze factor. CP happened during the AIDS crisis and the down-and-out youth culture that inspired writers like Gibson was chock full of dykes, crossdressers, trans people, and queers. Where do you think all the CP fashion comes from? :P
IRL, gender's where we're taking our first and biggest steps into transhumanism, one of the biggest themes in CP. People are not only swapping sexes, they're creating and defining their own, whether through medical innovations or social expression.
Most of the mods and cybernetics you can get in the game have a mechanical purpose, but most people don't need to be able to shrug off bullets or jump over cars - the vast majority of money is probably being spent on things everyday people want. It's not hard to imagine the possibilities.